β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) nrog cov khoom zoo.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau cov khoom no, thov xa cov ncauj lus kom ntxaws suav nrog CAS naj npawb, cov khoom npe, kom muaj nuj nqis rau peb.Thov hu rau:lchen@syncozymes.com
| Tshuaj npe | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Synonyms | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| CAS Nr | 53-59-8 |
| Molecular Luj | 743.41 ib |
| Molecular Formula | C21H28N7O17P3 |
| EINECS No. | 200-178-1 : kuv |
| cia temp. | Khaws nyob rau hauv qhov chaw tsaus, Inert cua, Khaws rau hauv lub freezer, hauv qab -20 ° C |
| solubility | H2O: 50 mg/mL, ntshiab, daj me ntsis |
| pka ua | pKa1 3,9;pKa2 6.1 (ntawm 25 ℃) |
| lw max | 260nm (lit.) |
| Merck | 14,6348 ib |
| EPA Tshuaj Registry System | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester nrog 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, sab hauv ntsev (53-59- 8) |
| Cov khoom kuaj | Specifications |
| Qhov tshwm sim | Dawb rau daj hmoov |
| Solubility | 200mg / ml hauv dej |
| pH tus nqi (100mg / ml) | 5.0 ~ 7.0 |
| UV Spectral Analysis 260nm thiab pH 7.5 | (18 ± 1.0) × 10³L/mol/cm |
| Cov ntsiab lus (los ntawm kev tsom xam enzymatic nrog G6PDH ntawm pH 7.5, siv spectrophotometer, abs.340nm, ntawm lub hauv paus tsis muaj dej) | ≥90.0% |
| Purity (los ntawm HPLC,% cheeb tsam) | ≥95.0% |
| Cov ntsiab lus dej (los ntawm KF) | ≤ 5% |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws nruj nreem kaw rau hauv qhov tsaus ntuj, kom ntev cia khaws cia ntawm 2 ~ 8 ℃.
NADP yog ib qho coenzyme, uas yog ib yam khoom uas nicotinamide adenine dinucleotide thiab phosphate molecule raug khi los ntawm ester daim ntawv cog lus, thiab dav dav.nyob rau hauv lub ntiaj teb biological.Nws cov khoom siv tshuaj, kev nqus spectrum, daim ntawv redox, thiab lwm yam zoo ib yam li NAD (Coenzyme I).NADP tuaj yeem siv dav hauv cov tshuaj tiv thaivcatalyzed los ntawm ntau yam cawv dehydrogenases, ketoreductases thiab lwm yam oxidoreductases.Xws li: nws tuaj yeem raug txo rau NADPH los ntawm ntau dehydrogenases xws liraws li 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Txawm li cas los xij, nws tsis tas yuav muaj peev xwm cuam tshuam nrog ntau tusdehydrogenases uas siv NAD, thiab nws tsis tuaj yeem ncaj qha oxidized los ntawm cov kab ua pa.Tsis zoo li NAD, nws muaj feem ntau hauv lub xeev txo qis hauv cov hlwb ntawm cov kab mob aerobic.
Raws li cov khoom siv, nws tuaj yeem muab faib ua cov qib hauv qab no: qib biotransformation, qib kuaj reagent, qib zaub mov noj qab haus huv.
Biotransformation qib: Nws tuaj yeem siv rau kev sib txuas ntawm cov tshuaj intermediates thiab APIs, feem ntau nrog catalytic enzymes, xws li ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), qabzib dehydrogenase (GDH), thiab lwm yam. Tos.
Diagnostic reagent qib: Nrog ntau yam kev kuaj mob enzymes, raws li cov khoom siv ntawm cov khoom siv kuaj mob.
Kev noj qab haus huv qib: Daim ntawv thov kev noj zaub mov ntxiv ntawm NADP feem ntau yog nyob rau hauv kev tshawb fawb thiab kev loj hlob.
