β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. yog lub tuam txhab tsim khoom thiab muab khoom ntawm β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) nrog cov khoom zoo. Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, muaj me me thiab ntau. Yog tias koj xav tau cov khoom no, thov xa cov ntaub ntawv ntxaws ntxaws suav nrog CAS tus lej, lub npe khoom, thiab ntau npaum li cas rau peb. Thov hu rau:lchen@syncozymes.com
| Lub Npe Tshuaj | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Cov lus txhais | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Tus lej CAS | 53-59-8 |
| Qhov Hnyav Molecular | 743.41 |
| Cov Qauv Molecular | C21H28N7O17P3 |
| EINECS No. | 200-178-1 |
| cia kub. | Khaws cia rau hauv qhov chaw tsaus ntuj, Inert huab cua, Khaws cia rau hauv lub tub yees, qis dua -20 ° C |
| kev yaj tau | H2O: 50 mg/mL, ntshiab, daj me ntsis |
| pka | pKa1 3.9; pKa2 6.1 (ntawm 25 ℃) |
| λmax | 260nm (lit.) |
| Merck | 14,6348 |
| EPA Lub Txheej Txheem Sau Npe Tshuaj | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester nrog 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, ntsev sab hauv (53-59-8) |
| Khoom Siv Kuaj | Cov Lus Qhia Tshwj Xeeb |
| Qhov tsos | Dawb rau daj hmoov |
| Kev yaj tau | 200mg / ml hauv dej |
| Tus nqi pH (100mg/ml) | 5.0 ~ 7.0 |
| Kev Tshuaj Xyuas Spectral UV εntawm 260 nm thiab pH 7.5 | (18±1.0) × 10³L/mol/cm2 |
| Cov ntsiab lus (los ntawm kev tshuaj xyuas enzymatic nrog G6PDH ntawm pH 7.5, siv spectrophotometer, abs.340nm, ntawm anhydrous basis) | ≥90.0% |
| Kev huv (los ntawm HPLC,% cheeb tsam) | ≥95.0% |
| Cov dej hauv (los ntawm KF) | ≤5% |
Pob:Lub raj mis, Lub hnab ntawv txhuas, 25kg / Cardboard nruas, lossis raws li tus neeg siv khoom xav tau.
Kev Khaws Cia:Khaws cia kom nruj rau hauv qhov tsaus ntuj, khaws cia rau ntawm 2 ~ 8 ℃ rau lub sijhawm ntev.
NADP yog ib qho coenzyme, uas yog ib yam khoom uas nicotinamide adenine dinucleotide thiab ib qho phosphate molecule raug khi los ntawm ib qho ester bond, thiab muaj dav davnyob rau hauv lub ntiaj teb biological. Nws cov khoom siv tshuaj lom neeg, cov spectrum nqus, daim ntawv redox, thiab lwm yam zoo ib yam li NAD (Coenzyme I). NADP tuaj yeem siv dav hauv kev tshuaj tiv thaivcatalyzed los ntawm ntau yam cawv dehydrogenases, ketoreductases thiab lwm yam oxidoreductases. Xws li: nws tuaj yeem txo qis rau NADPH los ntawm ntau yam dehydrogenases xws liua 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Txawm li cas los xij, nws tsis tas yuav muaj peev xwm cuam tshuam nrog ntau yamcov dehydrogenases uas siv NAD, thiab nws tsis tuaj yeem raug oxidized ncaj qha los ntawm cov saw hlau ua pa. Tsis zoo li NAD, nws feem ntau nyob rau hauv lub xeev txo qis hauv cov hlwb ntawm cov kab mob aerobic.
Raws li kev siv khoom, nws tuaj yeem muab faib ua cov qib hauv qab no: biotransformation qib, kuaj mob reagent qib, zaub mov noj qab haus huv qib.
Qib Biotransformation: Nws tuaj yeem siv rau kev tsim cov tshuaj intermediates thiab APIs, feem ntau nrog cov enzymes catalytic, xws li ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), thiab lwm yam. Tos.
Qib tshuaj reagent kuaj mob: Nrog ntau yam tshuaj enzymes kuaj mob, ua cov khoom siv raw ntawm cov khoom siv kuaj mob.
Qib khoom noj khoom haus kev noj qab haus huv: Daim ntawv thov kev noj haus ntxiv ntawm NADP feem ntau yog nyob rau hauv kev tshawb fawb thiab kev txhim kho.
