Bet-Nicotinamide Mononucleotide (NMN)
Tsis ntev los no, muaj xov xwm zoo hauv thaj chaw ntawm NMN - tom qab kev tshuaj xyuas nruj los ntawm pawg neeg tshaj lij ntawm US Food and Drug Administration (FDA) lub koom haum muaj cai, cov khoom siv NMN raw ntawm Shangke Biopharmaceutical (Shanghai) Co., Ltd. (tom qab no hu ua "Shangke Bio") tau txais kev pom zoo los ntawm Tebchaws Meskas FDA NDI kev pom zoo lees paub tias nws cov khoom siv NMN raw tuaj yeem siv tau hauv kev tsim khoom, kev muag khoom thiab kev txhawb nqa cov khoom noj khoom haus hauv Tebchaws Meskas, thiab tuaj yeem pom ntawm FDA lub vev xaib ua cov khoom siv tshiab, tus lej 1247.
FDA NDI yog lub kaw lus pov thawj tseem ceeb tshaj plaws hauv kev lag luam hauv Tebchaws Meskas. Kev tau txais daim ntawv pov thawj no tsis yog txhais tau tias kev nyab xeeb thiab zoo ntawm Shangke Bio cov khoom yoglees paub zoo heev, tab sis kuj yog qhov zoo rau kev txhim kho tus qauv ntawm kev lag luam NMN mus ntev.
| Lub Npe Tshuaj | β-Nicotinamide Mononucleotide |
| Cov lus txhais | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Tus lej CAS | 1094-61-7 |
| Qhov Hnyav Molecular | 334.22 |
| Cov Qauv Molecular | C11H15N2O8P |
| EINECS: | 214-136-5 |
| Qhov kub yaj | 166 ° C (dec.) |
| cia kub. | -20°C |
| kev yaj tau | DMSO (Me ntsis, Sov), Methanol (Me ntsis), Dej (Me ntsis) |
| daim ntawv | Khoom khov kho |
| xim | Dawb mus rau daj |
| Merck | 13,6697 |
| BRN | 3570187 |
| Kev Ruaj Ntseg: | Hygroscopic heev |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Khoom Siv Kuaj | Cov Lus Qhia Tshwj Xeeb |
| Qhov tsos | Dawb rau cov hmoov crystalline dawb |
| Cov ntsiab lus ntawm sodium | ≤1% |
| Tus nqi pH (100mg/ml) | 2.0~4.0 |
| Kev dawb huv | ≥99.0% |
| Cov dej ntsiab lus | ≤1% |
| Cov hlau hnyav | <10ppm |
| Arsenic | <0.5ppm |
| Cov hlau lead | <0.5ppm |
| Mercury | <0.1ppm |
| Cadmium | <0.5ppm |
| Cov tshuaj seem | Ethanol≤1000ppm |
| Tag Nrho Cov Kab Mob Aerobic | <750cfu/g |
| Poov xab & pwm | <25cfu/g |
| Tag nrho cov coliform | ≤0.92MPN/g |
| E. Coli | Tsis zoo |
| Kab mob Salmonella | Tsis zoo |
| Staph. Aureus | Tsis zoo |
| Kev Ntsuas (ntawm lub hauv paus anhydrous) | ≥99.0% |
| Tus nqi sieving | ≥95% |
| Qhov ceev ntawm cov khoom loj | Daim ntawv qhia txog cov ntaub ntawv |
Pob:Lub raj mis, Lub hnab ntawv txhuas, 25kg / Cardboard nruas, lossis raws li tus neeg siv khoom xav tau.
Kev Khaws Cia:Khaws cia rau hauv cov thawv kaw, tiv taus lub teeb, rau kev khaws cia ntev khaws cia ntawm 2 ~ 8 ° C lossis qis dua.
Nicotinamide Mononucleotide (NMN) yog ib qho tshiab ntawm vitamin B3 uas yog 1 kauj ruam ua ntej rau NAD + (Nicotinamide Adenine Dinucleotide). NMN yog thawj cellular NAD + restorer uas tau ua pov thawj tias muaj txiaj ntsig zoo los kho cov cell hauv vivo.
Nicotinamide Adenine Dinucleotide (NAD) yog ib qho ntawm cov molecule tseem ceeb thiab nthuav tshaj plaws hauv lub cev. Nws yog qhov xav tau rau ntau dua 500 qhov kev hloov pauv enzymatic thiab ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm yuav luag txhua qhov txheej txheem tseem ceeb ntawm lub cev (Ansari thiab Raghava, 2010). Qhov tseem ceeb tshaj plaws, nws yuav tso cai rau peb kom muaj kev noj qab haus huv thiab lub neej ntev dua.
Nicotinamide Adenine Dinucleotide (NAD) muaj nyob rau hauv nws daim ntawv oxidized (NAD +) lossis daim ntawv txo qis (NADH), uas yog cov cofactors tseem ceeb ntawm ntau tus oxireductases.
SyncoZyems yog thawj lub tuam txhab tsim khoom siv raw khoom uas tau txais kev pom zoo los ntawm FDA NDI NMN, thiab sawv cev rau FDA tus neeg ua haujlwm lees txais NMN ua ib yam khoom tshiab uas tuaj yeem pib lees txais thiab pom zoo rau cov khoom xyaw ntxiv rau kev noj haus hauv Tebchaws Meskas.
