Epoxide hydrolase (EH)
Lus piav qhia luv luv:
Hais txog epoxide hydrolase
EH yog ether hydrolase uas catalyze stereoselective hydrolysis ntawm racemic epoxides los tsim 1, 2-diol thiab optically active epoxides, uas yuav siv tau rau chiral daws teeb meem ntawm epoxides los yog kev npaj ntawm chiral diols.Lawv tau siv dav hauv tshuaj thiab lwm yam kev lag luam.Muaj 3 yam khoom epoxide hydrolases (Ntau li ES-EH-101～ES-EH-103) tsim los ntawm SyncoZymes.ES-EH yog ib qho cuab yeej siv tau los ua kom muaj kev sib txuas ntawm chiral alcohols los ntawm stereoselective hydrolysis ntawm aliphatic thiab aromatic epoxides.
Catalytic tshuaj tiv thaiv hom:
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E-Mail:lchen@syncozymes.com
| Enzymes | Khoom Code | Specification |
| Enzyme hmoov | ES-EH-101 ~ ES-EH-103 | ib txheej ntawm 3 Epoxide Hydrolases, 50 mg txhua 3 yam * 50mg / khoom, lossis lwm yam |
| Cov khoom siv tshuaj ntsuam xyuas (SynKit) | ES-EH-300 | ib txheej ntawm 3 Epoxide Hydrolases, 1 mg txhua 3 yam khoom * 1mg / khoom |
★ High substrate specification.
★ Muaj zog chiral selectivity.
★ Kev hloov pauv siab.
★ Tsawg los ntawm cov khoom lag luam.
★ Cov tshuaj tiv thaiv me me.
★ Ib puag ncig tus phooj ywg.
➢ Nquag, cov txheej txheem tshuaj tiv thaiv yuav tsum suav nrog substrate, tsis muaj tshuaj (pH zoo tshaj plaws) thiab ES-EH.
➢ Txhua yam ntawm ES-EHs sib haum rau ntau yam kev mob tshwm sim zoo yuav tsum tau kawm ib tus zuj zus.
➢ High concentration Substrate los yog khoom nrog tej zaum yuav inhibit ES-EH cov dej num.Txawm li cas los xij, qhov inhibition tuaj yeem daws tau los ntawm batch ntxiv ntawm substrate.
Piv txwv 1(1):
Khaws 2 xyoos qis dua -20 ℃.
Tsis txhob tiv tauj nrog huab cua xws li: kub siab, siab / qis pH thiab siab concentration organic hnyav.
1. Kim YH, Lee SH, Choi SH, et al.J Mol Catal B-Enzym, 2013, 89:48-51.
