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Ketoreductase (KRED)
Hais txog Ketoreductase
Enzymes: Yog macromolecular lom catalysts, feem ntau enzymes yog cov proteins.
Ketoreductase: Kuj hu ua "Carbonyl reductase", yog cov enzymes uas ua rau cov tshuaj tiv thaiv rov qab los ntawm aldehydes / ketones thiab cawv, thiab xav tau coenzymes li H transmitter xws li NADH lossis NADPH.Muaj peb pawg tseem ceeb ntawm KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), thiab Aldo-KetoReductases (AKRs).Cov kev ua haujlwm catalytic ntawm peb qhov zoo sib xws, tab sis cov qauv thiab cov khoom sib txawv heev.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Transaminase (ATA)
Hais txog transaminase
ATA los ntawm SyncoZymes: Muaj 66 yam khoom ATA enzyme (Number as ES-ATA-101 ~ ES-ATA-166) tsim los ntawm SyncoZymes.SZ-ATA yog ib qho cuab yeej muaj txiaj ntsig rau catalyze regio- thiab stereoselective synthesis ntawm chiral amines, amino acids thiab lawv cov derivatives los ntawm ntau yam aliphatic thiab aromatic ketoacids, aldehydes, ketones thiab ketoses.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Nitrilase (NWS)
Hais txog Nitrilase
ES-NITs: ncaj qha hloov cyanide pawg rau carboxyl pawg, npaj carboxylic acid, uas yog dav siv nyob rau hauv cov tshuaj, kev tiv thaiv ib puag ncig, tshuaj lom neeg kev lag luam, khoom noj khoom haus additive, textile, ua liaj ua teb thiab lwm yam liaj teb.
Muaj 40 hom Nitrilase (NIT) cov khoom (Ntau li ES-NIT-101 ~ ES-NIT-140) tsim los ntawm SyncoZymes.ES-NIT yog ib qho cuab yeej siv tau los ua kom cov khoom sib txuas ntawm chiral carboxylic acids los ntawm regio- thiab stereoselective hydrolysis ntawm ntau yam aliphatic thiab aromatic nitriles.Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Nitrile hydratase (NHT) hmoov
Hais txog ES-NHTs
ES-NHTs: ib chav kawm ntawm metalloenzyme, uas xaiv hydrate nitriles rau hauv cov thawj amide.Lawv tau dav siv tsis tau tsuas yog rau cov synthesis ntawm amino acids, amides, carboxylic acids thiab lawv derivatives, tab sis kuj rau kev npaj ntawm chiral tshuaj.Muaj 24 hom nitrile hydratases tsim los ntawm SyncoZymes (Tswj raws li ES-NHT-101～ES-NHT-124).
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Amidase (AMD)
AMD los ntawm SyncoZymes: Muaj 19 yam ntawm AMD cov khoom lag luam enzyme (Number as ES-AMD-101 ~ ES-AMD-119) tsim los ntawm SyncoZymes.SZ-AMD yog ib qho cuab yeej muaj txiaj ntsig rau catalyze regio- thiab stereoselective synthesis ntawm chiral carboxylic acids thiab lawv cov derivatives los ntawm ntau yam aliphatic thiab aromatic amides.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Ene reductase (ERED)
Hais txog ene reductase
ES-EREDs: Nyob rau tsev neeg ntawm cov laus daj enzymes uas xaiv txo C = C hauv α, β -unsaturated compounds nrog electron-absorbing pawg.Lawv tau siv dav hauv kev kawm txog cov amino acid derivatives, bioactive tshuaj, tshuaj intermediates, txuj lom thiab chiral blocks.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Oxynitrilases (HNL)
Hais txog oxynitrilases
ES-HNLs: Ib chav kawm enzyme uas enantioselectively catalyze ntxiv ntawm HCN rau aldehydes (ketones) kom tau R lossis S hom cyanide alcohols, uas tuaj yeem hloov tau yooj yim rau ntau hom tshuaj lossis tshuaj intermediates los ntawm kev siv tshuaj.
Muaj 29 yam khoom oxynitrilase (Number as ES-HNL-101～ES-HNL-129) tsim los ntawm SyncoZymes.SZ-HNL yog ib qho cuab yeej pab tau rau regio- thiab stereo- xaiv synthesis ntawm (R)-cyanohydrins los yog (S)-cyanohydrins los ntawm ntau yam aromatic, aliphatic thiab heterocyclic aldehydes los yog txawm ketones.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Nitro reductase (NTR)
Hais txog nitro reductase
ES-NTRs: Yog flavoenzymes uas catalyze NAD (P) H-nyob ntawm qhov txo qis ntawm nitro pawg ntawm nitroaromatic thiab nitroheterocyclic compounds rau hydroxylamino thiab / lossis amino derivatives.Lawv tau dav siv nyob rau hauv cov organic synthesis ntawm aromatic hydroxylamine thiab aromatic amine, qog kho mob, kuaj kab mob lom thiab degradation ntawm ib puag ncig cov pa phem.Muaj 12 hom Nitro reductase (NTR) cov khoom lag luam (Ntau li ES-NTR-101 ~ ES-NTR-112) tsim los ntawm SyncoZymes.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Ua tau zoo catalyze stereoselective ntxiv ntawm pub ketones rau receptor aldehydes.Ntxiv mus, cov tshuaj tiv thaiv tuaj yeem nqa tawm hauv cov kua dej ntawm nruab nrab pH yam tsis muaj kev tiv thaiv tshwj xeeb.Lawv nyob rau hauv chav kawm I aldolase, uas tsim Shiff puag hauv cov txheej txheem catalytic.Lub substrate yog covalently bonded nrog cov amino pawg ntawm lub active site los pib lub breakage thiab tsim ntawm daim ntawv cog lus.Qhov sib txawv ntawm DERAs thiab lwm yam aldolases yog tias cov substrates lawv catalyze yog aldehydes thiab tuaj yeem ua rau cov aldehydes tas li.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Hais txog CYP
ES-CYPs: Ib chav kawm ntawm redox enzymes nrog mercaptan-heme ua qhov chaw ua haujlwm rau catalyze oxygen hloov.Lawv yog cov terminal oxygenases thiab xav tau heme los qhib oxygen.
Cytochrome P450 monooxygenase catalyze oxidation, epoxidation thiab hydroxylation ntawm alkyl, hydroxylation thiab oxidation ntawm ammonia, oxidation ntawm sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination thiab dehalogenation.
Muaj 8 hom cytochrome P450 monooxygenase cov khoom lag luam (Ntau li ES-CYP-101～ES-CYP-108) tsim los ntawm SyncoZymes.Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Cawv oxidase (AOX)
Hais txog cawv oxidase
ES-AOXs: Cov enzymes no muaj peev xwm catalyze oxidation ntawm fatty alcohols los yog aryl-alcohols los tsim aldehydes.Lawv siv cov pa oxygen molecular tab sis tsis xav tau ib qho ntxiv cofactor, thiab hydrogen peroxide tsim.
Muaj 6 yam khoom siv cawv oxidases (Ntau li ES-AOX-101 ~ ES-AOX-106) tsim los ntawm SyncoZymes.ES-AOX101 thiab ES-AOX102 nyiam aliphatic cawv substrates, ES-AOX103 ~ ES-AOX105 nyiam cov ntxhiab tsw qab, thiab ES-AOX106 yog cov roj cholesterol oxidase.SZ-AOX yog cov cuab yeej siv tau los ua kom oxidation ntawm fatty alcohols lossis aryl-alcohols los tsim aldehydes.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Hais txog D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): ib qho enzyme uas tuaj yeem txo 2-keto acid rau hauv D-amino acid.Cov tshuaj tiv thaiv xav tau NADP(H) thiab inorganic ammonia pub (xws li ammonia lossis ammonium ion).Muaj 17 hom D-amino acid dehydrogenases (Ntau li ES-DAADH-101 ~ ES-DAADH-117) tsim los ntawm SyncoZymes.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
