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Transaldolase (TAL)
Txog Transaldolase
ES-TAL (Transaldolase): feem ntau yog hais txog threonine transaldolases, uas tuaj yeem ua rau muaj kev cuam tshuam los tsim cov β-hydroxyphenylalanine derivatives nrog threonine thiab benzaldehyde derivatives. TAL yog PLP dependent enzyme. Tsuas muaj 1 hom TAL enzyme khoom (Tus lej ua ES-TAL101) tsim los ntawm SyncoZymes, uas tuaj yeem siv los tsim cov β-hydroxyphenylalanine thiab nws cov derivatives.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Ketoreductase (KRED)
Txog Ketoreductase
Cov Enzymes: Yog cov catalysts macromolecular biological, feem ntau cov enzymes yog cov protein.
Ketoreductase: Kuj hu ua "Carbonyl reductase", yog cov enzymes uas catalyze qhov kev hloov pauv redox ntawm aldehydes / ketones thiab cawv, thiab xav tau coenzymes ua H transmitter xws li NADH lossis NADPH. Muaj peb pawg tseem ceeb ntawm KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), thiab Aldo-KetoReductases (AKRs). Cov haujlwm catalytic ntawm peb yam zoo sib xws, tab sis cov qauv thiab cov khoom sib txawv heev.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Transaminase (ATA)
Txog transaminase
ATA los ntawm SyncoZymes: Muaj 66 hom khoom ATA enzyme (Tus lej ua ES-ATA-101 ~ ES-ATA-166) tsim los ntawm SyncoZymes. SZ-ATA yog ib qho cuab yeej pab tau rau catalyze regio- thiab stereoselective synthesis ntawm chiral amines, amino acids thiab lawv cov derivatives los ntawm ntau yam aliphatic thiab aromatic ketoacids, aldehydes, ketones thiab ketoses.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Nitrilase (NIT)
Txog Nitrilase
ES-NITs: Hloov cov pab pawg cyanide ncaj qha mus rau pab pawg carboxyl, los npaj cov carboxylic acid, uas yog siv dav hauv tshuaj, kev tiv thaiv ib puag ncig, kev lag luam tshuaj lom neeg, cov khoom noj khoom haus ntxiv, textile, kev tsim khoom ua liaj ua teb thiab lwm yam teb.
Muaj 40 hom khoom Nitrilase (NIT) (Tus lej ua ES-NIT-101 ~ ES-NIT-140) tsim los ntawm SyncoZymes. ES-NIT yog ib qho cuab yeej pab tau rau kev ua kom cov chiral carboxylic acids los ntawm kev hydrolysis ntawm ntau yam aliphatic thiab aromatic nitriles.Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Txog ES-NHTs
ES-NHTs: ib chav kawm ntawm metalloenzyme, uas xaiv hydrate nitriles rau hauv cov thawj amide sib xws. Lawv siv dav tsis yog rau kev tsim cov amino acids, amides, carboxylic acids thiab lawv cov derivatives, tab sis kuj rau kev npaj cov tshuaj chiral. Muaj 24 hom nitrile hydratases tsim los ntawm SyncoZymes (Tus lej li ES-NHT-101 ～ ES-NHT-124).
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Amidase (AMD)
AMD los ntawm SyncoZymes: Muaj 19 hom khoom AMD enzyme (Tus lej li ES-AMD-101 ~ ES-AMD-119) tsim los ntawm SyncoZymes. SZ-AMD yog ib qho cuab yeej pab tau rau catalyze regio- thiab stereoselective synthesis ntawm chiral carboxylic acids thiab lawv cov derivatives los ntawm ntau yam aliphatic thiab aromatic amides.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Ene reductase (ERED)
Txog ene reductase
ES-EREDs: Koom nrog tsev neeg ntawm cov enzymes daj qub uas xaiv txo C = C hauv α, β -unsaturated compounds nrog electron-absorbing pawg. Lawv siv dav hauv kev kawm txog amino acid derivatives, bioactive substances, pharmaceutical intermediates, spices thiab chiral blocks.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Cov tshuaj Oxynitrilases (HNL)
Txog cov tshuaj oxynitrilases
ES-HNLs: Ib hom enzyme uas enantioselectively catalyze qhov ntxiv ntawm HCN rau aldehydes (ketones) kom tau R lossis S hom cyanide alcohols, uas tuaj yeem hloov pauv mus ua ntau hom tshuaj lossis tshuaj nruab nrab los ntawm kev siv tshuaj lom neeg.
Muaj 29 hom khoom oxynitrilase (Tus lej ua ES-HNL-101 ~ ES-HNL-129) tsim los ntawm SyncoZymes. SZ-HNL yog ib qho cuab yeej pab tau rau kev tsim cov (R)-cyanohydrins lossis (S)-cyanohydrins los ntawm ntau yam aromatic, aliphatic thiab heterocyclic aldehydes lossis txawm tias ketones hauv thaj chaw thiab stereo.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Nitro reductase (NTR)
Txog nitro reductase
ES-NTRs: Yog cov flavoenzymes uas ua rau NAD(P)H-dependent txo cov nitro pawg ntawm nitroaromatic thiab nitroheterocyclic compounds rau hydroxylamino thiab/lossis amino derivatives. Lawv siv dav hauv kev tsim cov organic ntawm aromatic hydroxylamine thiab aromatic amine, kev kho mob qog noj ntshav, kev kuaj pom biological thiab kev puas tsuaj ntawm cov pa phem ib puag ncig. Muaj 12 hom Nitro reductase (NTR) khoom (Tus lej ua ES-NTR-101~ES-NTR-112) tsim los ntawm SyncoZymes.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Muaj peev xwm ua kom muaj kev sib ntxiv ntawm cov ketones pub dawb rau cov receptor aldehydes. Ntxiv mus, qhov kev sib xyaw ua ke tuaj yeem ua tiav hauv cov kua dej ntawm pH nruab nrab yam tsis muaj kev tiv thaiv tshwj xeeb. Lawv koom nrog chav kawm I aldolase, uas tsim Shiff puag hauv cov txheej txheem catalytic. Lub substrate yog covalently bonded nrog cov amino pawg ntawm qhov chaw nquag kom pib qhov tawg thiab tsim ntawm daim ntawv cog lus. Qhov sib txawv ntawm DERAs thiab lwm yam aldolases yog tias cov substrates uas lawv catalyze yog aldehydes thiab tuaj yeem dhau los ua aldehydes condensation tas mus li.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Txog CYP
ES-CYPs: Ib pawg ntawm cov enzymes redox nrog mercaptan-heme ua lub hauv paus tseem ceeb los ua kom cov pa oxygen hloov pauv. Lawv yog cov oxygenases kawg thiab xav tau heme los ua kom cov pa oxygen ua haujlwm.
Cytochrome P450 monooxygenase catalyze qhov oxidation, epoxidation thiab hydroxylation ntawm alkyl, hydroxylation thiab oxidation ntawm ammonia, oxidation ntawm sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination thiab dehalogenation.
Muaj 8 hom cytochrome P450 monooxygenase khoom (Tus lej li ES-CYP-101 ～ ES-CYP-108) tsim los ntawm SyncoZymes.Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Cawv oxidase (AOX)
Txog cawv oxidase
ES-AOXs: Cov enzymes no muaj peev xwm ua kom cov roj alcohols lossis aryl-alcohols ua aldehydes. Lawv siv cov pa oxygen molecular tab sis tsis xav tau cov cofactor ntxiv sab nraud, thiab hydrogen peroxide tsim tawm.
Muaj 6 hom cawv oxidases khoom (Tus lej li ES-AOX-101 ~ ES-AOX-106) tsim los ntawm SyncoZymes. ES-AOX101 thiab ES-AOX102 nyiam aliphatic cawv substrates, ES-AOX103 ~ ES-AOX105 nyiam aromatic cawv substrates, thiab ES-AOX106 yog cholesterol oxidase. SZ-AOX yog ib qho cuab yeej pab tau los catalyze oxidation ntawm fatty cawv lossis aryl-alcohols los tsim aldehydes.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
