SyncoZymes

cov khoom

Oxynitrilases (HNL)

Lus piav qhia luv luv:

Hais txog oxynitrilases

ES-HNLs: Ib chav kawm enzyme uas enantioselectively catalyze ntxiv ntawm HCN rau aldehydes (ketones) kom tau R lossis S hom cyanide alcohols, uas tuaj yeem hloov tau yooj yim rau ntau hom tshuaj lossis tshuaj intermediates los ntawm kev siv tshuaj.
Muaj 29 yam khoom oxynitrilase (Number as ES-HNL-101~ES-HNL-129) tsim los ntawm SyncoZymes.SZ-HNL yog ib qho cuab yeej pab tau rau regio- thiab stereo- xaiv synthesis ntawm (R)-cyanohydrins los yog (S)-cyanohydrins los ntawm ntau yam aromatic, aliphatic thiab heterocyclic aldehydes los yog txawm ketones.
Catalytic tshuaj tiv thaiv hom:

Oxynitrilases HNL2

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E-Mail:lchen@syncozymes.com


Product Detail

Khoom cim npe

Product Information:

Oxynitrilases HNL
Enzymes Khoom Code Specification
Enzyme hmoov ES-HNL-101 ~ ES-HNL-129 ib txheej ntawm 29 oxynitrilases, 50 mg txhua 29 yam khoom * 50mg / khoom, lossis lwm yam
Cov khoom siv tshuaj ntsuam xyuas (SynKit) ES-HNL-1800 ib txheej ntawm 18 (S)-oxynitrilases, 1 mg txhua 18 yam khoom * 1mg / khoom
Cov khoom siv tshuaj ntsuam xyuas (SynKit) ES-HNL-1100 ib txheej ntawm 11 (R)-oxynitrilases, 1 mg txhua 11 yam * 1mg / khoom

Qhov zoo:

★ High substrate specification.
★ Muaj zog chiral selectivity.
★ Kev hloov pauv siab.
★ Tsawg los ntawm cov khoom lag luam.
★ Cov tshuaj tiv thaiv me me.
★ Ib puag ncig tus phooj ywg.

Cov lus qhia rau kev siv:

➢ Nquag, cov tshuaj tiv thaiv yuav tsum muaj cov substrate (aldehydes / ketones, HCN), buffer tov (zoo tshuaj tiv thaiv pH) thiab cov enzymes.
➢ Tag nrho cov ES-HNL tuaj yeem kuaj tau raws li cov txheej txheem tshuaj tiv thaiv saum toj no lossis nrog HNL Kev Ntsuas Cov Khoom Siv (SynKit HNL).
➢ Txhua yam ntawm ES-HNLs sib haum rau ntau yam kev xav tau zoo yuav tsum tau kawm ib tus zuj zus.
➢ High concentration Substrate los yog khoom nrog tej zaum yuav inhibit ES-HNL cov dej num.Txawm li cas los xij, qhov inhibition tuaj yeem daws tau los ntawm batch ntxiv ntawm substrate.

Piv txwv daim ntawv thov:

Piv txwv 1(1):

Oxynitrilases HNL3

Cia:

Khaws 2 xyoos qis dua -20 ℃.

Nco ntsoov:

Tsis txhob tiv tauj nrog huab cua xws li: kub siab, siab / qis pH thiab siab concentration organic hnyav.

Cov ntaub ntawv:

1 Langermann J, Guterl JK, Pohl M, et al.Bioprocess Biosyst Eng, 2008, 31:155-161.


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