Ketoreductase (KRED)
KRED los ntawm SyncoZymes: Muaj 191 hom KRED enzyme cov khoom lag luam (Tus lej li ES-KRED-101 ~ ES-KRED-291) tsim los ntawm SyncoZymes.SZ-KRED tuaj yeem siv dav hauv regio- thiab stereoselective txo qis ntawm aldehydes, beta-ketone esters, α-ketone esters thiab ketones.
Catalytic tshuaj tiv thaiv hom:
| Enzymes | Khoom Code | Specification |
| Enzyme hmoov | Enzyme hmoov | ib txheej ntawm 187 Ketoreductases, 50 mg txhua 187 yam khoom * 50mg / khoom, lossis lwm yam |
| Cov khoom siv tshuaj ntsuam xyuas (SynKit) | ES-KRED-18100 | ib txheej ntawm 181 Ketoreductases, 1 mg txhua 181 yam khoom * 1mg / khoom |
★ High substrate specification.
★ Muaj zog chiral selectivity.
★ High conversion efficiency.
★ Tsawg los ntawm cov khoom lag luam.
★ Cov tshuaj tiv thaiv me me.
★ Ib puag ncig tus phooj ywg.
➢ Kev tshuaj xyuas Enzyme yuav tsum tau ua rau cov substrates tshwj xeeb vim yog cov substrate tshwj xeeb, thiab tau txais ib qho enzyme uas catalyzes lub hom phiaj substrate nrog cov nyhuv catalytic zoo tshaj plaws.
➢ Tsis txhob tiv tauj nrog cov xwm txheej hnyav xws li: qhov kub thiab txias, pH siab / qis thiab cov kuab tshuaj organic nrog siab concentration.
➢ Nquag, cov tshuaj tiv thaiv yuav tsum muaj xws li substrate, buffer solution, coenzymes (NAD(H) los yog NADP(H)), coenzyme regeneration system (xws li qabzib thiab qabzib dehydrogenase).
➢ KRED yuav tsum muab ntxiv rau qhov kawg ntawm cov tshuaj tiv thaiv kab mob, tom qab pH thiab kub tau hloov kho rau cov tshuaj tiv thaiv.
➢ Txhua yam KRED muaj ntau yam kev pom zoo, yog li txhua tus ntawm lawv yuav tsum tau kawm ntxiv ib tus zuj zus.
Piv txwv 1(1):
Piv txwv 2(2):
1. Li Z., Liu WD, Chen X, e tal.Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, e tal.Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
