Imine reductase (IRED)

Kev Piav Qhia Luv:

Txog Imine reductase

ES-IRED: Ib chav kawm ntawm cov enzymes uas catalyze qhov kev txo qis ntawm C = N daim ntawv cog lus rau CN daim ntawv cog lus. Nws yog rau redox enzyme, nrog coenzyme NADPH rau kev thauj mus los hydrogen. Raws li qhov kev nyiam chiral ntawm cov khoom, lawv tuaj yeem faib ua R-IRED thiab S-IRED. Syncozymes tsim 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), uas tuaj yeem siv dav hauv kev txo qis regioselective thiab stereoselective ntawm imines los npaj chiral amines.
Hom tshuaj tiv thaiv catalytic:

Imine reductase (IRED) 2

Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526

Email:lchen@syncozymes.com

Xa email rau peb

Cov Khoom Qhia Txog Khoom

Cov Cim Npe Khoom

Cov Ntaub Ntawv Khoom:

Cov Enzymes	Cov Cai Khoom	Cov Lus Qhia Tshwj Xeeb
Hmoov Enzyme	ES-IRED-101~ ES-IRED-114	Ib pawg ntawm 14 Imine Reductase, 50 mg txhua yam
Cov Khoom Siv Tshuaj Xyuas Enzyme 96-Qhov	ES-IRED-1400	ib pawg ntawm 14 Imine Reductase, 1 mg txhua yam

Cov txiaj ntsig:

★ Kev tshwj xeeb ntawm cov substrate siab.
★ Muaj zog xaiv chiral.
★ Kev hloov pauv siab heev.
★ Cov khoom tsis muaj txiaj ntsig tsawg dua.
★ Cov mob ua xua me me.
★ Ib puag ncig zoo.

Cov lus qhia rau kev siv:

➢ Feem ntau, lub kaw lus tshuaj tiv thaiv yuav tsum muaj cov khoom siv substrate, buffer solution, enzyme, coenzyme, thiab coenzyme regeneration system.
➢ Yuav tsum kawm txog txhua yam ES-IREDs uas sib raug rau ntau yam xwm txheej zoo tshaj plaws ntawm kev teb.
➢ Cov khoom siv uas muaj cov tshuaj ntau dhau los yog cov khoom uas muaj cov tshuaj no yuav ua rau ES-IRED tsis ua haujlwm. Txawm li cas los xij, qhov kev txwv no yuav raug txo los ntawm kev ntxiv cov tshuaj ntxiv rau hauv.

Piv txwv ntawm daim ntawv thov:

Piv txwv 1 (Kev tsim cov chiral 2-methyl pyrrolidine)⁽¹⁾:

Piv txwv 2 (Kev tsim cov amine theem nrab)⁽²⁾:

Piv txwv 3 (Kev txo qis ntawm Cyclic Imines)⁽³⁾:

Kev Khaws Cia:

Khaws cia rau 2 xyoos hauv qab -20 ℃.

Ceeb Toom:

Tsis txhob kov cov xwm txheej hnyav xws li: kub heev, pH siab / qis thiab cov kuab tshuaj organic siab.

Cov ntaub ntawv siv los ua piv txwv:

1. Scheller PN, Fademrecht S, Hofelzer S, thiab al. ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, thiab lwm tus. ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al. Adv. Synth. Catal. 2015, 357, 1692-1696.

Yav dhau los: Hydroaminase (HAM)

Tom ntej no: Ketoreductase (KRED)

Sau koj cov lus ntawm no thiab xa tuaj rau peb