Ketoreductase (KRED)
KRED los ntawm SyncoZymes: Muaj 191 hom khoom KRED enzyme (Tus lej ua ES-KRED-101 ~ ES-KRED-291) tsim los ntawm SyncoZymes. SZ-KRED tuaj yeem siv dav hauv kev txo qis hauv cheeb tsam thiab stereoselective ntawm aldehydes, beta-ketone esters, α-ketone esters thiab ketones.
Hom tshuaj tiv thaiv catalytic:
| Cov Enzymes | Cov Cai Khoom | Cov Lus Qhia Tshwj Xeeb |
| Hmoov Enzyme | Hmoov Enzyme | ib pawg ntawm 187 Ketoreductases, 50 mg txhua 187 yam khoom * 50mg / yam khoom, lossis lwm yam ntau npaum li cas |
| Cov Khoom Siv Tshuaj Ntsuam Xyuas (SynKit) | ES-KRED-18100 | ib pawg ntawm 181 Ketoreductases, 1 mg txhua 181 yam khoom * 1mg / yam khoom |
★ Kev tshwj xeeb ntawm cov substrate siab.
★ Muaj zog xaiv chiral.
★ Kev hloov pauv siab heev.
★ Cov khoom tsis muaj txiaj ntsig tsawg dua.
★ Cov mob ua xua me me.
★ Ib puag ncig zoo.
➢ Yuav tsum tau kuaj xyuas enzyme rau cov substrates tshwj xeeb vim yog qhov tshwj xeeb ntawm cov substrate, thiab tau txais cov enzyme uas ua rau lub substrate catalytic zoo tshaj plaws.
➢ Tsis txhob kov cov xwm txheej hnyav xws li: kub heev, pH siab/qis thiab cov kuab tshuaj organic uas muaj concentration siab.
➢ Feem ntau, lub kaw lus tshuaj tiv thaiv yuav tsum muaj cov khoom siv substrate, cov kua buffer, coenzymes (NAD (H) lossis NADP (H)), coenzyme regeneration system (piv txwv li glucose thiab glucose dehydrogenase).
➢ Yuav tsum ntxiv KRED rau hauv qhov system tshuaj tiv thaiv tom qab pH thiab qhov kub tau hloov kho rau qhov xwm txheej tshuaj tiv thaiv.
➢ Txhua hom KRED muaj ntau yam kev mob tshwm sim zoo tshaj plaws, yog li txhua tus ntawm lawv yuav tsum tau kawm ntxiv ib tus zuj zus.
Piv txwv 1(1):
Piv txwv 2(2):
1. Li Z., Liu WD, Chen X, e tal. Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, e tal. Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
