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Cov tshuaj Oxynitrilases (HNL)
Txog cov tshuaj oxynitrilases
ES-HNLs: Ib hom enzyme uas enantioselectively catalyze qhov ntxiv ntawm HCN rau aldehydes (ketones) kom tau R lossis S hom cyanide alcohols, uas tuaj yeem hloov pauv mus ua ntau hom tshuaj lossis tshuaj nruab nrab los ntawm kev siv tshuaj lom neeg.
Muaj 29 hom khoom oxynitrilase (Tus lej ua ES-HNL-101 ~ ES-HNL-129) tsim los ntawm SyncoZymes. SZ-HNL yog ib qho cuab yeej pab tau rau kev tsim cov (R)-cyanohydrins lossis (S)-cyanohydrins los ntawm ntau yam aromatic, aliphatic thiab heterocyclic aldehydes lossis txawm tias ketones hauv thaj chaw thiab stereo.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Nitro reductase (NTR)
Txog nitro reductase
ES-NTRs: Yog cov flavoenzymes uas ua rau NAD(P)H-dependent txo cov nitro pawg ntawm nitroaromatic thiab nitroheterocyclic compounds rau hydroxylamino thiab/lossis amino derivatives. Lawv siv dav hauv kev tsim cov organic ntawm aromatic hydroxylamine thiab aromatic amine, kev kho mob qog noj ntshav, kev kuaj pom biological thiab kev puas tsuaj ntawm cov pa phem ib puag ncig. Muaj 12 hom Nitro reductase (NTR) khoom (Tus lej ua ES-NTR-101~ES-NTR-112) tsim los ntawm SyncoZymes.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Muaj peev xwm ua kom muaj kev sib ntxiv ntawm cov ketones pub dawb rau cov receptor aldehydes. Ntxiv mus, qhov kev sib xyaw ua ke tuaj yeem ua tiav hauv cov kua dej ntawm pH nruab nrab yam tsis muaj kev tiv thaiv tshwj xeeb. Lawv koom nrog chav kawm I aldolase, uas tsim Shiff puag hauv cov txheej txheem catalytic. Lub substrate yog covalently bonded nrog cov amino pawg ntawm qhov chaw nquag kom pib qhov tawg thiab tsim ntawm daim ntawv cog lus. Qhov sib txawv ntawm DERAs thiab lwm yam aldolases yog tias cov substrates uas lawv catalyze yog aldehydes thiab tuaj yeem dhau los ua aldehydes condensation tas mus li.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Txog CYP
ES-CYPs: Ib pawg ntawm cov enzymes redox nrog mercaptan-heme ua lub hauv paus tseem ceeb los ua kom cov pa oxygen hloov pauv. Lawv yog cov oxygenases kawg thiab xav tau heme los ua kom cov pa oxygen ua haujlwm.
Cytochrome P450 monooxygenase catalyze qhov oxidation, epoxidation thiab hydroxylation ntawm alkyl, hydroxylation thiab oxidation ntawm ammonia, oxidation ntawm sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination thiab dehalogenation.
Muaj 8 hom cytochrome P450 monooxygenase khoom (Tus lej li ES-CYP-101 ～ ES-CYP-108) tsim los ntawm SyncoZymes.Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Cawv oxidase (AOX)
Txog cawv oxidase
ES-AOXs: Cov enzymes no muaj peev xwm ua kom cov roj alcohols lossis aryl-alcohols ua aldehydes. Lawv siv cov pa oxygen molecular tab sis tsis xav tau cov cofactor ntxiv sab nraud, thiab hydrogen peroxide tsim tawm.
Muaj 6 hom cawv oxidases khoom (Tus lej li ES-AOX-101 ~ ES-AOX-106) tsim los ntawm SyncoZymes. ES-AOX101 thiab ES-AOX102 nyiam aliphatic cawv substrates, ES-AOX103 ~ ES-AOX105 nyiam aromatic cawv substrates, thiab ES-AOX106 yog cholesterol oxidase. SZ-AOX yog ib qho cuab yeej pab tau los catalyze oxidation ntawm fatty cawv lossis aryl-alcohols los tsim aldehydes.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Txog D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): ib qho enzyme uas tuaj yeem txo 2-keto acid mus rau hauv D-amino acid sib xws. Cov tshuaj tiv thaiv xav tau NADP (H) thiab cov inorganic ammonia donor (xws li ammonia lossis ammonium ion). Muaj 17 hom D-amino acid dehydrogenases (Tus lej ua ES-DAADH-101 ~ ES-DAADH-117) tsim los ntawm SyncoZymes.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Esterase & Lipase (PLE & CALB)
Txog Esterase & Lipase
ES-PLEs: Ib pawg hydrolases uas ua rau muaj kev tsim thiab tawg ntawm cov ester bonds. Lawv tuaj yeem koom nrog ntau hom kev tshuaj lom neeg, xws li esterification, transesterification thiab hydrolysis. Lawv siv dav hauv ntau qhov chaw xws li kev ua zaub mov, kev lag luam tshuaj lom neeg, biomedicine, chiral tshuaj thiab kev kho mob ib puag ncig.
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Txog epoxide hydrolase
EH yog ether hydrolase uas catalyze lub stereoselective hydrolysis ntawm racemic epoxides los tsim 1, 2-diol thiab optically active epoxides, uas tuaj yeem siv rau kev daws teeb meem chiral ntawm epoxides lossis kev npaj ntawm chiral diols. Lawv siv dav hauv kev kho mob thiab lwm yam teb. Muaj 3 hom epoxide hydrolases khoom (Tus lej li ES-EH-101 ～ ES-EH-103) tsim los ntawm SyncoZymes. ES-EH yog ib qho cuab yeej pab tau los catalyze lub synthesis ntawm chiral alcohols los ntawm stereoselective hydrolysis ntawm aliphatic thiab aromatic epoxides.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Txog Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH ua rau lub dehydrogenation ntawm ammonium formate tsim cov pa roj carbon dioxide thiab ammonia, thiab txo NAD rau NADH nrog NAD ua electron receptor. FDH feem ntau siv rau kev tsim cov coenzyme NADH. Muaj 4 hom khoom FDH enzyme (ES-FDH-101 ~ ES-FDH-104) tsim los ntawm SyncoZymes, ntawm cov ES-FDH102 muaj kev ua haujlwm siab tshaj plaws thiab yog FDH uas pom zoo tshaj plaws.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Txog Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH ua rau cov glucose dehydrogenation los tsim cov gluconic acid (lactone), thiab txo NAD(P)+ rau NAD(P)H, nrog NAD(P)+ ua electron receptor. GDH feem ntau siv rau kev rov ua dua coenzyme NAD(P)H hauv cov teb biocatalysis nrog lwm cov enzyme tseem ceeb. Muaj 10 hom GDH enzyme khoom (ES-GDH-101~ES-GDH-110) tsim los ntawm SyncoZymes, ntawm cov ES-GDH110 muaj kev ua haujlwm siab tshaj plaws thiab yog GDH uas pom zoo tshaj plaws.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Txog Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO catalyze qhov oxidative deamination ntawm monoamines los tsim hydrogen peroxide, ammonia thiab cov aldehydes sib xws. Hauv cov txheej txheem catalytic, oxygen yog qhov tsim nyog ua oxidant. Muaj 6 hom MAO enzyme khoom (Tus lej li ES-MAO-101 ~ ES-MAO-106) tsim los ntawm SyncoZymes, uas tuaj yeem siv rau hauv oxidative deamination ntawm monoamine compounds.
Hom tshuaj tiv thaiv catalytic:
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Txog Lactate dehydrogenase
Muaj 1 hom khoom LDH enzyme (Tus lej ua ES-LDH) tsim los ntawm SyncoZymes. LDH tuaj yeem ua rau muaj kev txo qis ntawm pyruvate mus rau L-lactic acid, lossis txo qis ntawm lwm cov α-keto acids zoo sib xws. Hauv cov txheej txheem ntawm catalysis, NADH yog qhov tsim nyog ua tus thauj hydrogen.
Hom tshuaj tiv thaiv Lactate dehydrogenasecatalytic
Xov tooj ntawm tes/Wechat/WhatsApp: +86-13681683526
Email:lchen@syncozymes.com
