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Oxynitrilases (HNL)
Hais txog oxynitrilases
ES-HNLs: Ib chav kawm enzyme uas enantioselectively catalyze ntxiv ntawm HCN rau aldehydes (ketones) kom tau R lossis S hom cyanide alcohols, uas tuaj yeem hloov tau yooj yim rau ntau hom tshuaj lossis tshuaj intermediates los ntawm kev siv tshuaj.
Muaj 29 yam khoom oxynitrilase (Number as ES-HNL-101～ES-HNL-129) tsim los ntawm SyncoZymes.SZ-HNL yog ib qho cuab yeej pab tau rau regio- thiab stereo- xaiv synthesis ntawm (R)-cyanohydrins los yog (S)-cyanohydrins los ntawm ntau yam aromatic, aliphatic thiab heterocyclic aldehydes los yog txawm ketones.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Nitro reductase (NTR)
Hais txog nitro reductase
ES-NTRs: Yog flavoenzymes uas catalyze NAD (P) H-nyob ntawm qhov txo qis ntawm nitro pawg ntawm nitroaromatic thiab nitroheterocyclic compounds rau hydroxylamino thiab / lossis amino derivatives.Lawv tau dav siv nyob rau hauv cov organic synthesis ntawm aromatic hydroxylamine thiab aromatic amine, qog kho mob, kuaj kab mob lom thiab degradation ntawm ib puag ncig cov pa phem.Muaj 12 hom Nitro reductase (NTR) cov khoom lag luam (Ntau li ES-NTR-101 ~ ES-NTR-112) tsim los ntawm SyncoZymes.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Ua tau zoo catalyze stereoselective ntxiv ntawm pub ketones rau receptor aldehydes.Ntxiv mus, cov tshuaj tiv thaiv tuaj yeem nqa tawm hauv cov kua dej ntawm nruab nrab pH yam tsis muaj kev tiv thaiv tshwj xeeb.Lawv nyob rau hauv chav kawm I aldolase, uas tsim Shiff puag hauv cov txheej txheem catalytic.Lub substrate yog covalently bonded nrog cov amino pawg ntawm lub active site los pib lub breakage thiab tsim ntawm daim ntawv cog lus.Qhov sib txawv ntawm DERAs thiab lwm yam aldolases yog tias cov substrates lawv catalyze yog aldehydes thiab tuaj yeem ua rau cov aldehydes tas li.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Hais txog CYP
ES-CYPs: Ib chav kawm ntawm redox enzymes nrog mercaptan-heme ua qhov chaw ua haujlwm rau catalyze oxygen hloov.Lawv yog cov terminal oxygenases thiab xav tau heme los qhib oxygen.
Cytochrome P450 monooxygenase catalyze oxidation, epoxidation thiab hydroxylation ntawm alkyl, hydroxylation thiab oxidation ntawm ammonia, oxidation ntawm sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination thiab dehalogenation.
Muaj 8 hom cytochrome P450 monooxygenase cov khoom lag luam (Ntau li ES-CYP-101～ES-CYP-108) tsim los ntawm SyncoZymes.Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Cawv oxidase (AOX)
Hais txog cawv oxidase
ES-AOXs: Cov enzymes no muaj peev xwm catalyze oxidation ntawm fatty alcohols los yog aryl-alcohols los tsim aldehydes.Lawv siv cov pa oxygen molecular tab sis tsis xav tau cov cofactor sab nraud, thiab hydrogen peroxide tsim.
Muaj 6 yam khoom siv cawv oxidases (Ntau li ES-AOX-101 ~ ES-AOX-106) tsim los ntawm SyncoZymes.ES-AOX101 thiab ES-AOX102 nyiam aliphatic cawv substrates, ES-AOX103 ~ ES-AOX105 nyiam cov ntxhiab tsw qab, thiab ES-AOX106 yog cov roj cholesterol oxidase.SZ-AOX yog cov cuab yeej siv tau los ua kom oxidation ntawm fatty alcohols lossis aryl-alcohols los tsim aldehydes.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Hais txog D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): ib qho enzyme uas tuaj yeem txo 2-keto acid rau hauv D-amino acid.Cov tshuaj tiv thaiv xav tau NADP(H) thiab inorganic ammonia pub (xws li ammonia lossis ammonium ion).Muaj 17 hom D-amino acid dehydrogenases (Ntau li ES-DAADH-101 ~ ES-DAADH-117) tsim los ntawm SyncoZymes.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Esterase & Lipase (PLE & CALB)
Hais txog Esterase & Lipase
ES-PLEs: Ib chav kawm ntawm hydrolases uas catalyze tsim thiab tawg ntawm ester bonds.Lawv tuaj yeem koom nrog ntau hom tshuaj lom neeg biochemical, xws li esterification, transesterification thiab hydrolysis.Lawv tau siv dav hauv ntau qhov chaw xws li kev ua zaub mov, kev lag luam tshuaj, biomedicine, chiral tshuaj thiab kev kho ib puag ncig.
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Epoxy hydrolase (EH)
Hais txog epoxide hydrolase
EH yog ether hydrolase uas catalyze stereoselective hydrolysis ntawm racemic epoxides los tsim 1, 2-diol thiab optically active epoxides, uas yuav siv tau rau chiral daws teeb meem ntawm epoxides los yog kev npaj ntawm chiral diols.Lawv tau siv dav hauv tshuaj thiab lwm yam kev lag luam.Muaj 3 yam khoom epoxide hydrolases (Ntau li ES-EH-101～ES-EH-103) tsim los ntawm SyncoZymes.ES-EH yog ib qho cuab yeej siv tau los ua kom muaj kev sib txuas ntawm chiral alcohols los ntawm stereoselective hydrolysis ntawm aliphatic thiab aromatic epoxides.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Txog Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH catalyze lub dehydrogenation ntawm ammonium formate los tsim carbon dioxide thiab ammonia, thiab txo NAD rau NADH nrog NAD ua electron receptor.FDH feem ntau siv rau kev rov tsim dua ntawm coenzyme NADH.Muaj 4 yam ntawm FDH enzyme khoom (ES-FDH-101 ~ ES-FDH-104) tsim los ntawm SyncoZymes, ntawm cov uas ES-FDH102 muaj kev ua haujlwm siab tshaj plaws thiab yog qhov feem ntau pom zoo FDH.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Hais txog Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH catalyze lub dehydrogenation ntawm qabzib los tsim gluconic acid (lactone), thiab txo NAD(P) + rau NAD(P)H, nrog NAD(P) + ua electron receptor.GDH feem ntau yog siv rau kev tsim dua tshiab ntawm coenzyme NAD (P)H hauv biocatalysis teb nrog lwm cov enzyme tseem ceeb.Muaj 10 hom GDH enzyme khoom (ES-GDH-101 ~ ES-GDH-110) tsim los ntawm SyncoZymes, ntawm cov uas ES-GDH110 muaj qhov ua haujlwm siab tshaj plaws thiab yog cov lus pom zoo GDH.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Txog Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO catalyze lub oxidative deamination ntawm monoamines los tsim hydrogen peroxide, ammonia thiab coj aldehydes.Nyob rau hauv cov txheej txheem catalytic, oxygen yog tsim nyog raws li oxidant.Muaj 6 hom MAO enzyme khoom (Ntau li ES-MAO-101～ES-MAO-106) tsim los ntawm SyncoZymes, uas tuaj yeem siv rau hauv oxidative deamination ntawm monoamine compounds.
Catalytic tshuaj tiv thaiv hom:
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Hais txog Lactate dehydrogenase
Muaj 1 yam khoom LDH enzyme (Number as ES-LDH) tsim los ntawm SyncoZymes.LDH tuaj yeem ua rau txo qis ntawm pyruvate rau L-lactic acid, lossis txo qis ntawm lwm yam zoo li α-keto acids.Nyob rau hauv tus txheej txheem ntawm catalysis, NADH yog tsim nyog raws li hydrogen transporter.
Lactate dehydrogenasecatalytic cov tshuaj tiv thaiv hom
Txawb/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
